You guys, I freaking looove niacinamide (aka vitamin B3). IMO (and according to, like, 99.9 percent of dermatologists), it’s one of the true skincare greats—like in the same category as retinol and vitamin C. It’s because niacinamide not only (1) normalizes your skin’s oil production to keep pores clear and breakouts in check, but also (2) regulates pigment-making cells to fade hyperpigmentation, (3) soothes redness with its anti-inflammatory properties, (4) protects from free-radical damage, AND (5) boosts your skin’s hydration level. Impressive, right? And even better, it’s safe to use on any and all skin types. So go ahead and check out one of these 12 best niacinamide serums to see for yourself why I’m truly obsessed with it.
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Best Soothing Niacinamide Serum
Dr. Dennis Gross Skincare Stress Rescue Super Serum
True to its name, this niacinamide serum is perfect for anyone with inflamed, irritated, or stressed-out skin. In addition to soothing niacinamide, it uses ashwaganda and goji fruit extracts to make skin more resilient and better equipped to protect itself from skin stressors, like pollution, blue light, and debris.
Best Niacinamide Serum for Rough Texture
Shani Darden Skin Care Texture Reform
LAs-based facialist Shani Darden‘s Texture Reform serum is loved by celebs (like Shay Mitchell and Chrissy Teigen) for good reason: It makes skin look ridiculously plump and smooth. It’s all thanks to niacinamide, lactic acid, aloe vera, and a mild form of retinol. Together they gently exfoliate, shrink pores, even out texture, and soften skin.
Best Niacinamide Serum for Hyperpigmentation
Peter Thomas Roth Pro Strength Niacinamide Discoloration Treatment
If you’re dealing with melasma, dark spots, or post-inflammatory hyperpigmentation, def give this brightening niacinamide serum from Peter Thomas Roth a try. In addition to niacinamide, it uses a combo of skin brighteners (like tranexamic acid, kojic acid, and alpha arbutin) to suppresses excess melanin production to keep skin looking even and bright.
Best Niacinamide Serum for Fine Lines
Olay Wrinkle Correction Serum with Vitamin B3+ Collagen Peptides
Best Niacinamide Gel Serum
Sobel Skin Rx 15% Niacinamide Gel Serum
Best Niacinamide Serum for Daytime
Epi.logic by Dr. Jeanniton Daily Dose Vitamin C + Multivitamin Defense Serum
Along with niacinamide, this potent serum contains a cocktail of antioxidants—like vitamin B5, C, E, and ferulic acid—making it the perfect first-step in your morning skincare routine. A few drops protect skin from environmental aggressors and free radical damage for a healthy glow.
Best Niacinamide Serum for Acne-Prone Skin
The Ordinary Niacinamide 10% + Zinc 1%
Unlike other harsh acne-treating products with, say, salicylic acid or benzoyl peroxide, this 10 percent niacinamide serum with zinc won’t dry out your skin or cause redness and flaking. What it will do? Reduce oil production, unclog pores, and cut down on inflammation.
Best Hydrating Niacinamide Serum
Skin Inc Vitamin B3+ Serum
All skin types can benefit from the hydrating effects of this lightweight niacinamide serum. In addition to vitamin B3, it uses hyaluronic acid and glycerin—two humectants that draw moisture to the skin—to hydrate and plump your face without leaving behind any greasy or tacky residue.
Best Mattifying Niacinamide Serum
The Inkey List Niacinamide
Oily skin types, listen up (and feel free to throw away your blotting papers while you’re at it). This mattifying niacinamide serum regulates your skin’s sebum production so you never look overly greasy or shiny. And regulated oil can also mean fewer blackheads and breakouts.
Best Niacinamide Booster Serum
Paula’s Choice 10% Niacinamide Booster
You don’t have to radically switch up your skincare routine to reap the benefits of niacinamide. Just mix a few drops of this niacinamide booster serum with your current day cream, night cream, or sunscreen to experience all the glow-boosting benefits of the antioxidant.
This Multitasking Niacinamide Serum
Murad Revitalixir Recovery Serum
For when you are hungover, haven’t slept, or just feel stressed AF and your skin is paying the price, try this multitasking niacinamide serum. It brightens, hydrates, and de-puffs to give your tired skin a healthy glow.
Best Natural Niacinamide Serum
Kristina Holey + Marie Veronique Soothing B3 Serum
A few months ago, my sensitive skin had a serious freakout after a bad reaction to a product I was testing, and I swear this gentle niacinamide serum made everything better. The formula is full of anti-inflammatory niacinamide and all-natural plant extracts—plus it’s free-from potential skin irritants (like synthetic dyes or fragrances).
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